The Audi S4, available in the Sedan and Avant versions, employs the most powerful engine in the line - the 3.0 TFSI with 245 kW (333 hp) and 440 Nm (324.53 lb-ft) torque. The Sedan's average fuel consumption is a mere 8.0 liters per 100 km (29.40 US mpg) - with an impressive performance: The Audi S4 accelerates in 5.0 seconds from zero to 100 km/h (62.14 mph) and achieves an electronically limited maximum speed of 250 km/h (155.34 mph).

The modified Audi S4 is identifiable from the changes to the headlights, the bumpers, the air inlets and colors. The interior also contains subtle changes in appearance. The S sport suspension and 18-inch wheels featured on the S4 deliver outstanding road grip.